Welcome to our web application to explore epidemiological and economic scenarios of CYD-TDV vaccination.
This application has been designed as a complement to the manuscript: Model-based assessment of public health impact and cost-effectiveness of dengue vaccination following screening for prior exposure.
We calculated the benefits of 10 years of routine vaccination of 9-year-old children with CYD-TDV following screening for prior exposure. These scenarios were simulated using a parameterized agent-based model of the city of Iquitos. The public health impact of vaccination is expressed as the proportion of cases averted by comparing the outcomes of simulations with and without vaccination. The economic evaluation of the cost-effectiveness is expressed as the maximum unit cost of screening that would result in the intervention still being cost-effective, given a fixed cost of the vaccine.
This app was designed to explore the impact of vaccination with a wide variety of transmission and economic scenarios. Follow the tab "Results by Screening Sensitivity and Specificity" to evaluate the impact of vaccination in a broad range of properties of the screening test. Follow the tab "Results by Transmission Setting" to evaluate the impact of vaccination with a selection of properties from commercially available screening tests. To evaluate vaccination in a specific setting, adjust the transmission intensity and vaccination properties using the sliders. The top figures will show the public health impact of the specified scenario. The bottom figures will show the cost-effectiveness of the vaccination programs determined by the sensitivity and specificity of screening.
Feel free to report bugs to guido.espana@nd.edu
Welcome to our web application to explore epidemiological and economic scenarios of CYD-TDV vaccination.
This application has been designed as a complement to the manuscript: Model-based assessment of public health impact and cost-effectiveness of dengue vaccination following screening for prior exposure.
We calculated the benefits of 10 years of routine vaccination of 9-year-old children with CYD-TDV following screening for prior exposure. These scenarios were simulated using a parameterized agent-based model of the city of Iquitos. The public health impact of vaccination is expressed as the proportion of cases averted by comparing the outcomes of simulations with and without vaccination. The economic evaluation of the cost-effectiveness is expressed as the maximum unit cost of screening that would result in the intervention still being cost-effective, given a fixed cost of the vaccine.
This app was designed to explore the impact of vaccination with a wide variety of transmission and economic scenarios. Follow the tab "Results by Screening Sensitivity and Specificity" to evaluate the impact of vaccination in a broad range of properties of the screening test. Follow the tab "Results by Transmission Setting" to evaluate the impact of vaccination with a selection of properties from commercially available screening tests. To evaluate vaccination in a specific setting, adjust the transmission intensity and vaccination properties using the sliders. The top figures will show the public health impact of the specified scenario. The bottom figures will show the cost-effectiveness of the vaccination programs determined by the sensitivity and specificity of screening.
Feel free to report bugs to guido.espana@nd.edu